5/24/2025
Last update
5/24/2025
Reviewed By
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 5 Researches
7.6
USERS' SCORE
Good
Based on 11 Reviews
8.2
Supplement Facts
Serving Size: 2 Tablets
Amount Per Serving
%DV
Vitamin D2 (as Ergocalciferol - a vegetarian source)
10 mcg (400 IU)
50%
Calcium (from Calcium Citrate)
600 mg
46%
Magnesium (from Magnesium Oxide and Magnesium Aspartate)
300 mg
71%
Zinc (from Zinc AAC*)
15 mg
136%
Copper (from Copper AAC*)
1 mg
111%
Manganese (from Manganese AAC*)
5 mg
217%
Top Medical Research Studies
8
Urinary factors impact kidney stone risk
We undertook a thorough analysis of 24-hour urine collections from over 6,200 participants to explore how various urinary factors contribute to kidney stone formation.
Our findings revealed that higher levels of urine volume, citrate, potassium, magnesium, and uric acid were linked to a lower risk of developing stones. Conversely, increased levels of calcium, oxalate, phosphorus, and sodium were associated with a higher risk.
Interestingly, urine acidity did not seem to play a role. Our research highlighted the complexity and varying importance of these urinary factors regarding their relationship with stone formation.
Our findings revealed that higher levels of urine volume, citrate, potassium, magnesium, and uric acid were linked to a lower risk of developing stones. Conversely, increased levels of calcium, oxalate, phosphorus, and sodium were associated with a higher risk.
Interestingly, urine acidity did not seem to play a role. Our research highlighted the complexity and varying importance of these urinary factors regarding their relationship with stone formation.
Read More
7
We explored the effects of a low-calorie, high-citrate beverage named Moonstone on patients with calcium kidney stones. Administered twice daily, this drink increased urine citrate levels and pH while reducing calcium oxalate levels compared to plain water.
While this drink was well-received and tolerated by participants, the benefits seen are similar to those from potassium-magnesium citrate. Although promising, more research is needed to confirm its efficacy in reducing kidney stones in broader patient groups.
While this drink was well-received and tolerated by participants, the benefits seen are similar to those from potassium-magnesium citrate. Although promising, more research is needed to confirm its efficacy in reducing kidney stones in broader patient groups.
Read More
7
We investigated whether calcium citrate treatment helps prevent kidney stones over a long period. Our analysis followed patients with calcium stones for up to 12 years, focusing on how medical therapy, like calcium citrate, impacts stone recurrence.
We found that patients treated with calcium citrate, particularly those forming calcium-oxalate stones, showed lower recurrence rates after about five years. This delay in seeing benefits is crucial for understanding how we can plan future treatments.
We found that patients treated with calcium citrate, particularly those forming calcium-oxalate stones, showed lower recurrence rates after about five years. This delay in seeing benefits is crucial for understanding how we can plan future treatments.
Read More
Most Useful Reviews
7.5
Prevents kidney stones
4 people found this helpful
Best Absorbable Form of Calcium Why did I choose this particular calcium? Because my dietitian advised me to take calcium citrate as it is the least likely to contribute to the formation of kidney stones. This is the most optimal form of calcium. Additionally, the composition also contains vitamin D2, zinc, copper, magnesium and manganese. However, consider this if you are consuming other supplements to avoid overdose! It is recommended to take two tablets daily, ideally at different times. For instance, in the morning and afternoon. At night - it's not recommended, due to rapid mineral salt release from the body. Adults only should use this. The only drawback for me is the size of the oblong-shaped tablets - 2.4 cm long. I also struggle to swallow pills, needing to drink and eat to prevent choking on them. If my review is helpful, please like it 👍🙂
Read More
7.5
Highly absorbed calcium
3 people found this helpful
Good calcium! Calcium citrate is the optimal dosage form, absorbed by the body much better than calcium carbonate (which is more commonly sold in pharmacies). A key feature of calcium citrate is its low ability to form kidney stones, which is significant with prolonged use. As mineral salts are released from the body more quickly at night, it's advisable to take calcium supplements after lunch and in the evening. It's best to drink it with water and never tea!
Read More
9
Energy cycle assistance
1 people found this helpful
Excellent! Calcium citrate not only has high digestibility but offers numerous advantages. It reduces calcium excretion in urine, prevents kidney stones by alkalising urine, and aids in the absorption of vitamin C and minerals while participating in cellular energy cycles. I am pleased with my purchase and its benefits.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 5 Researches
7.6
- All Researches
8
Magnesium supplements benefit kidney stone formers
We evaluated how magnesium oxide and magnesium citrate supplements affect kidney stone formers with high oxalate levels. In a rigorous study with 90 participants, we found that both supplements helped lower oxalate excretion and calcium oxalate supersaturation when compared to a placebo.
Notably, magnesium citrate showed even stronger results, especially for those with normal urine magnesium levels. While both options are effective in reducing potential kidney stone risks, magnesium citrate may offer an edge in certain patients.
Notably, magnesium citrate showed even stronger results, especially for those with normal urine magnesium levels. While both options are effective in reducing potential kidney stone risks, magnesium citrate may offer an edge in certain patients.
Read More
8
Urinary factors impact kidney stone risk
We undertook a thorough analysis of 24-hour urine collections from over 6,200 participants to explore how various urinary factors contribute to kidney stone formation.
Our findings revealed that higher levels of urine volume, citrate, potassium, magnesium, and uric acid were linked to a lower risk of developing stones. Conversely, increased levels of calcium, oxalate, phosphorus, and sodium were associated with a higher risk.
Interestingly, urine acidity did not seem to play a role. Our research highlighted the complexity and varying importance of these urinary factors regarding their relationship with stone formation.
Our findings revealed that higher levels of urine volume, citrate, potassium, magnesium, and uric acid were linked to a lower risk of developing stones. Conversely, increased levels of calcium, oxalate, phosphorus, and sodium were associated with a higher risk.
Interestingly, urine acidity did not seem to play a role. Our research highlighted the complexity and varying importance of these urinary factors regarding their relationship with stone formation.
Read More
8
We investigated how combining sulfated polysaccharides with potassium citrate could inhibit calcium oxalate (CaOx) crystal formation and protect kidney cells.
Our study utilized various additive groups to compare their effectiveness. Excitingly, the combination of sulfated compounds and potassium citrate showed an impressive increase in their protective effects on renal cells and their capability to prevent crystal aggregation.
Particularly, the SDLP-Kcit combination stood out as an effective option for treating kidney stones, outpacing standalone treatments. This suggests a promising avenue for future kidney stone therapies.
Our study utilized various additive groups to compare their effectiveness. Excitingly, the combination of sulfated compounds and potassium citrate showed an impressive increase in their protective effects on renal cells and their capability to prevent crystal aggregation.
Particularly, the SDLP-Kcit combination stood out as an effective option for treating kidney stones, outpacing standalone treatments. This suggests a promising avenue for future kidney stone therapies.
Read More
7
We investigated whether calcium citrate treatment helps prevent kidney stones over a long period. Our analysis followed patients with calcium stones for up to 12 years, focusing on how medical therapy, like calcium citrate, impacts stone recurrence.
We found that patients treated with calcium citrate, particularly those forming calcium-oxalate stones, showed lower recurrence rates after about five years. This delay in seeing benefits is crucial for understanding how we can plan future treatments.
We found that patients treated with calcium citrate, particularly those forming calcium-oxalate stones, showed lower recurrence rates after about five years. This delay in seeing benefits is crucial for understanding how we can plan future treatments.
Read More
7
We explored the effects of a low-calorie, high-citrate beverage named Moonstone on patients with calcium kidney stones. Administered twice daily, this drink increased urine citrate levels and pH while reducing calcium oxalate levels compared to plain water.
While this drink was well-received and tolerated by participants, the benefits seen are similar to those from potassium-magnesium citrate. Although promising, more research is needed to confirm its efficacy in reducing kidney stones in broader patient groups.
While this drink was well-received and tolerated by participants, the benefits seen are similar to those from potassium-magnesium citrate. Although promising, more research is needed to confirm its efficacy in reducing kidney stones in broader patient groups.
Read More
User Reviews
USERS' SCORE
Good
Based on 11 Reviews
8.2
- All Reviews
- Positive Reviews
- Negative Reviews
7.5
Prevents kidney stones
4 people found this helpful
Best Absorbable Form of Calcium Why did I choose this particular calcium? Because my dietitian advised me to take calcium citrate as it is the least likely to contribute to the formation of kidney stones. This is the most optimal form of calcium. Additionally, the composition also contains vitamin D2, zinc, copper, magnesium and manganese. However, consider this if you are consuming other supplements to avoid overdose! It is recommended to take two tablets daily, ideally at different times. For instance, in the morning and afternoon. At night - it's not recommended, due to rapid mineral salt release from the body. Adults only should use this. The only drawback for me is the size of the oblong-shaped tablets - 2.4 cm long. I also struggle to swallow pills, needing to drink and eat to prevent choking on them. If my review is helpful, please like it 👍🙂
Read More
7.5
Highly absorbed calcium
3 people found this helpful
Good calcium! Calcium citrate is the optimal dosage form, absorbed by the body much better than calcium carbonate (which is more commonly sold in pharmacies). A key feature of calcium citrate is its low ability to form kidney stones, which is significant with prolonged use. As mineral salts are released from the body more quickly at night, it's advisable to take calcium supplements after lunch and in the evening. It's best to drink it with water and never tea!
Read More
9
Energy cycle assistance
1 people found this helpful
Excellent! Calcium citrate not only has high digestibility but offers numerous advantages. It reduces calcium excretion in urine, prevents kidney stones by alkalising urine, and aids in the absorption of vitamin C and minerals while participating in cellular energy cycles. I am pleased with my purchase and its benefits.
Read More
9
No kidney stones
Drank for prevention. All is well. No kidney stones have arisen. Feeling good, you can take it.
Read More
7.5
Normalised calcium levels
Excellent product! I ordered this for my mother, who is prone to kidney stones and had worsening osteoporosis. After about a year of use, her lab results showed normalised calcium levels and improved tests for bone metabolism, halting osteoporosis progression. A fantastic product!
Read More
Frequently Asked Questions
6
Low kidney stone risk
Calcium citrate is among the most digestible forms of this mineral and aids in preventing kidney stones! My mother and I took calcium citrate and it lasted about a month. It's best consumed in the afternoon, around 7 or 8 pm. It’s a good form of calcium, but I won't repurchase it. Calcium works best with magnesium and vitamin D3, hence I’ll focus on combination preparations moving forward. I won’t lower the rating, as it was my conscious decision to buy calcium citrate.
7.5
Normalised calcium levels
Excellent product! I ordered this for my mother, who is prone to kidney stones and had worsening osteoporosis. After about a year of use, her lab results showed normalised calcium levels and improved tests for bone metabolism, halting osteoporosis progression. A fantastic product!
9
No kidney stones
Drank for prevention. All is well. No kidney stones have arisen. Feeling good, you can take it.
9
Energy cycle assistance
1 people found this helpful
Excellent! Calcium citrate not only has high digestibility but offers numerous advantages. It reduces calcium excretion in urine, prevents kidney stones by alkalising urine, and aids in the absorption of vitamin C and minerals while participating in cellular energy cycles. I am pleased with my purchase and its benefits.
7.5
Highly absorbed calcium
3 people found this helpful
Good calcium! Calcium citrate is the optimal dosage form, absorbed by the body much better than calcium carbonate (which is more commonly sold in pharmacies). A key feature of calcium citrate is its low ability to form kidney stones, which is significant with prolonged use. As mineral salts are released from the body more quickly at night, it's advisable to take calcium supplements after lunch and in the evening. It's best to drink it with water and never tea!
7.5
Prevents kidney stones
4 people found this helpful
Best Absorbable Form of Calcium Why did I choose this particular calcium? Because my dietitian advised me to take calcium citrate as it is the least likely to contribute to the formation of kidney stones. This is the most optimal form of calcium. Additionally, the composition also contains vitamin D2, zinc, copper, magnesium and manganese. However, consider this if you are consuming other supplements to avoid overdose! It is recommended to take two tablets daily, ideally at different times. For instance, in the morning and afternoon. At night - it's not recommended, due to rapid mineral salt release from the body. Adults only should use this. The only drawback for me is the size of the oblong-shaped tablets - 2.4 cm long. I also struggle to swallow pills, needing to drink and eat to prevent choking on them. If my review is helpful, please like it 👍🙂
9
Recommended for osteoporosis
5 people found this helpful
My mother has been taking this for six months, and she consumes one tablet daily for osteoporosis prevention. It works well and doesn't cause issues associated with other calcium forms. As a pharmacist, I recommend everyone choose calcium citrate to avoid potential kidney complications from inorganic salts that can lead to stones.
8
Magnesium supplements benefit kidney stone formers
We evaluated how magnesium oxide and magnesium citrate supplements affect kidney stone formers with high oxalate levels. In a rigorous study with 90 participants, we found that both supplements helped lower oxalate excretion and calcium oxalate supersaturation when compared to a placebo.
Notably, magnesium citrate showed even stronger results, especially for those with normal urine magnesium levels. While both options are effective in reducing potential kidney stone risks, magnesium citrate may offer an edge in certain patients.
Notably, magnesium citrate showed even stronger results, especially for those with normal urine magnesium levels. While both options are effective in reducing potential kidney stone risks, magnesium citrate may offer an edge in certain patients.
7
We investigated whether calcium citrate treatment helps prevent kidney stones over a long period. Our analysis followed patients with calcium stones for up to 12 years, focusing on how medical therapy, like calcium citrate, impacts stone recurrence.
We found that patients treated with calcium citrate, particularly those forming calcium-oxalate stones, showed lower recurrence rates after about five years. This delay in seeing benefits is crucial for understanding how we can plan future treatments.
We found that patients treated with calcium citrate, particularly those forming calcium-oxalate stones, showed lower recurrence rates after about five years. This delay in seeing benefits is crucial for understanding how we can plan future treatments.
8
Urinary factors impact kidney stone risk
We undertook a thorough analysis of 24-hour urine collections from over 6,200 participants to explore how various urinary factors contribute to kidney stone formation.
Our findings revealed that higher levels of urine volume, citrate, potassium, magnesium, and uric acid were linked to a lower risk of developing stones. Conversely, increased levels of calcium, oxalate, phosphorus, and sodium were associated with a higher risk.
Interestingly, urine acidity did not seem to play a role. Our research highlighted the complexity and varying importance of these urinary factors regarding their relationship with stone formation.
Our findings revealed that higher levels of urine volume, citrate, potassium, magnesium, and uric acid were linked to a lower risk of developing stones. Conversely, increased levels of calcium, oxalate, phosphorus, and sodium were associated with a higher risk.
Interestingly, urine acidity did not seem to play a role. Our research highlighted the complexity and varying importance of these urinary factors regarding their relationship with stone formation.
7
We explored the effects of a low-calorie, high-citrate beverage named Moonstone on patients with calcium kidney stones. Administered twice daily, this drink increased urine citrate levels and pH while reducing calcium oxalate levels compared to plain water.
While this drink was well-received and tolerated by participants, the benefits seen are similar to those from potassium-magnesium citrate. Although promising, more research is needed to confirm its efficacy in reducing kidney stones in broader patient groups.
While this drink was well-received and tolerated by participants, the benefits seen are similar to those from potassium-magnesium citrate. Although promising, more research is needed to confirm its efficacy in reducing kidney stones in broader patient groups.
8
We investigated how combining sulfated polysaccharides with potassium citrate could inhibit calcium oxalate (CaOx) crystal formation and protect kidney cells.
Our study utilized various additive groups to compare their effectiveness. Excitingly, the combination of sulfated compounds and potassium citrate showed an impressive increase in their protective effects on renal cells and their capability to prevent crystal aggregation.
Particularly, the SDLP-Kcit combination stood out as an effective option for treating kidney stones, outpacing standalone treatments. This suggests a promising avenue for future kidney stone therapies.
Our study utilized various additive groups to compare their effectiveness. Excitingly, the combination of sulfated compounds and potassium citrate showed an impressive increase in their protective effects on renal cells and their capability to prevent crystal aggregation.
Particularly, the SDLP-Kcit combination stood out as an effective option for treating kidney stones, outpacing standalone treatments. This suggests a promising avenue for future kidney stone therapies.
References
- Taheri M, Jalali S, Borumandnia N, Tavasoli S, Basiri A, et al. Effect of magnesium oxide or citrate supplements on metabolic risk factors in kidney stone formers with idiopathic hyperoxaluria: a randomized clinical trial. Magnes Res. 2024;37:12. 10.1684/mrh.2024.0524
- Ruchi R, Di Valerio EA, Bozorgmehri S, Bacchus MW, Canales BK, et al. Pharmacotherapy and Stone Mineral Subtype Influence Long-Term Recurrence Rates in Calcium Stone Formers. Kidney360. 2024;5:1333. 10.34067/KID.0000000000000526
- Ferraro PM, Taylor EN, Curhan GC. 24-Hour Urinary Chemistries and Kidney Stone Risk. Am J Kidney Dis. 2024;84:164. 10.1053/j.ajkd.2024.02.010
- Goldfarb DS, Modersitzki F, Asplin JR, Nazzal L. Effect of a high-citrate beverage on urine chemistry in patients with calcium kidney stones. Urolithiasis. 2023;51:96. 10.1007/s00240-023-01468-w
- Liu JH, Ouyang JM. Synergistic inhibition of calcium oxalate crystal formation and synergistic protection of HK-2 cells from crystal damage by sulfated polysaccharide and potassium citrate. Biomater Sci. 2023;11:3524. 10.1039/d3bm00087g
